ALDH2 (NM_000690) Human 3' UTR Clone

Specifications

Product Data
Product Name	ALDH2 (NM_000690) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ALDH-E2; ALDHI; ALDM
ACCN	NM_000690
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC206080 3’UTR clone of NM_000690 The sequence shown below is from the reference sequence of NM_000690. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACAGTCAAAGTGCCTCAGAAGAACTCATAAGAATCATGCAAGCTTCCTCCCTCAGCCATTGATGGAAAG TTCAGCAAGATCAGCAACAAAACCAAGAAAAATGATCCTTGCGTGCTGAATATCTGAAAAGAGAAATTT TTCCTACAAAATCTCTTGGGTCAAGAAAGTTCTAGAATTTGAATTGATAAACATGGTGGGTTGGCTGAG GGTAAGAGTATATGAGGAACCTTTTAAACGACAACAATACTGCTAGCTTTCAGGATGATTTTTAAAAAA TAGATTCAAATGTGTTATCCTCTCTCTGAAACGCTTCCTATAACTCGAGTTTATAGGGGAAGAAAAAGC TATTGTTTACAATTATATCACCATTAAGGCAACTGCTACACCCTGCTTTGTATTCTGGGCTAAGATTCA TTAAAAACTAGCTGCTCTTAACTTACTGGGTAACTCTTTGTCCATCTCAATAACCAAAGGAAGGTGGGC ATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAAGCCGAGGCGGGTGGATCACTCGAGGTCAGGAG TTTGAGACCAGCCTGGCCAACGTAGTGAAACCCTGTCTCTCACTAAAAATACACAAATTAGGCAGTCAT GGTGGCTGGCACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAAAATTGGTTGAACCTGGGAGGT GGAGGTTGCAGTGAGTGGAGATCATGCCACTGCACTCCAGCCTGGGAGTCAGAGCGAGACTCCATCTCA AAAAAAGTAAATAAATGAAATAGCCTAAGGAAATGCTGGCAGGCAGTAATGATATGGCACACTGGATAT GATTTCTGCCCCTCCTCTGCTGTGGGTAAACAGCTTCTGTTTCATGCATTTACTTTTTTATTTTAATTA CACCAATAAGAATGTGCTTGAATGTTTCATGCATTTAATTTGTTTCATGCATTTAACTTCTGGCCTGTT TACCTGTAGCAGGCTCTGAGATGTGCTCTAGAGACAGAACCTAAACATGATGCCCAAGAGAGGGGAGAG ATACTGAATGTCCAATGTTCTCAAATTTTTTTTTTTTTTTTTTTTGAGACAGGGTCTTGCTCTGCCATC CAGGCTGGAGTGCAGTGGCACGATCATAGCTCACTGCTGCCTCGACCTCCTGGGCTCAAATGATCCTCC TGCTTCAGCTTCCTGGGCTAATGTTTGTATTTTTTGTGGAGATGGGACTTTGTTATGTTGCCCAGGCTG TTTTCAAACTCCTGGACTCAAGTGATCCTCCCGCCTTAGCCTCCTAAGGTGCTGGGATTACAGGTGTGA GCCACTGTGCCCAATTCAGTTCTCAGTAAAAACTTGATCAGGCCAAATGAAAGTGACATGGGCCAATTT CATAATAGATTGATTTGGAAACCAGATGTCAATTTACTTACTTTAAGTGAGATCTGTATCTTCAGTAAC CAGACCTCTTGAGTCTCCCACCCAGAACACTATCTTCCTCTAGTCAAGATACCTGGCAAAGGCCGGGCA CAGTGGCTCACGCCTATAATTCCAGCACTTTGGGAGGCCAAGGTGGGTGGGTCACCTGAGGTTGGGAGT TCGAGACCAGCCTGACCAACAGGGAGAAACCCCATCTCTACTGAAAATACAAAAAAAAAAAAAAAAACT AGCCGGGCATGGTGGCTCATGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAA CCTGGGAGGCAGAGGTTGCAGTGAGCCAAGATTGCTCCATTGTACTCCAGCCTGGGCAACAAGAGAGAA ACTCCGTCTCAAAATATAAATAAATAAGAAAAAGAAGAAATGGAAGCTGGGTTCAAGAGGGCAATCAGC AGTCTCTACCATCATGTGAAACACCACTCTGTGATTTGAGTCTTGACAATGTATTTTCTTTTTTTTTTT CTTCTTTTTTTTTTGAGACTGAGTCTCGGTCTGTCGCCCAGGCTGGAGTGCAGTGACGTGATCTTGGC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000690.4
Synonyms	ALDH-E2; ALDHI; ALDM
Summary	This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2016]
Locus ID	217
MW	75.5

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