Phospholipase C epsilon 1 (PLCE1) (NM_016341) Human 3' UTR Clone
CAT#: SC206072
3' UTR clone of phospholipase C epsilon 1 (PLCE1) transcript variant 1 for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
Cited in 1 publication. |
Product images
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经常一起买 (2)
Specifications
Product Data | |
Product Name | Phospholipase C epsilon 1 (PLCE1) (NM_016341) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | NPHS3; PLCE; PPLC |
ACCN | NM_016341 |
Insert Size | 2000 bp |
Sequence Data |
>SC206072 3’UTR clone of NM_016341
The sequence shown below is from the reference sequence of NM_016341. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCCAGTGACACAATGGATTACCGACAGTGACTAAGGGCAGCATGTTTAACCCAGGTGAAGATCTTTAAG CAAGAAGTTAAAGAGTGAACATGGTGGAAAAAATATAATTATTTTCATCAGACTTAAACTGGAAATTGA TGATTTCTGAACTGAAGCCTTCACACATGTGAGATCCATGCTGAGGAGAAGCAAAATGGCACAGGGCTA GTTGCCACCAACCAATTTACTGATGAATGAAGCCCAGGGGACTGCCATTTTATAAATGTCAGCAGTTGG AAAAATCGTCACGAATTGACTTAGAGCAAGGGTCAGCAAGCTTGTCTGTAAAGGGCCAAACAGTAAATA TTTTAGGGCTGGGGGCCATAAAATATGTTGCAACCACCCAATTCTGCCATTGTAGTGCAAAAGCAGCCA TAGACAACACATACATGAACGAACGTGGCTGTATTCCAATAAAACTTTATTTATGGACACTGAAATTGG AATTTCATATATTTTTCACATGTCACAAATACTCTTGTTTTGACTTTTTTTCAACCATTTAAAAACTTA AAAACTATTCTTAATTCAGGGGCCATACAAAAACAGGTGGCAGGCTAGATTTGGCCCAAGGACCTTAAT TTGCCAACACAACTAAGAGAAGAGAACTGGGAACAAGGAGCACAAAGATCTGAAAACAGGAAAGGAAGT TTAGCCATACATTTTATGGCCGAGAATTAGAAGCTTAGAATTAGAAGCTTTGGGGCATTTCAAGTGTAA ATATGTCCTATAACATAAGAGTCATTAAAATTCAATTTAGTTCCTGTATTGTGTACCACAGTGCACTCC TCTTTAGGATTTTTTTACATATAGAAATAATATTGGGTTTTTTTTAAGGTTATTGCCTATTCAGTTAAT AGGGTTGCTTTAAAAAAGGTTATTGCTTAATCATAGATTAGATTACTCATTTTTGGTTTTCAAAATGAA TTTAGAATGACGTATAATTTAATATCTACTGAATTGCAATGTCTTAACAAGAAACCTAACAATTTTTTA AAGCAAAAGTAGATTGAGTTGGCGTTTAAATTTATTTTGCAAGGTTTGTACTGACACTATACTTATATA TTTATTATACATCGCTCTCTTGATATTGCCATGGATTAGAAGCATTAGTTCTCAGTACTTGAAGACAAA CTTCTAAAAAGAAAATATATGCTCTGAACATCTGAAATGGGCTAGACTTTCAAGTAAAATTGCTTCATT TCTCATTAACTGAAGAGCTATTGATCCAAGTCATACTTGCCATTTAATGTAAATTATTTTTAAACTTTG CTGTACAAAACCATTAAGTGTAAAGGATTCTTCATATTCTTAGTATGAAGCAAATTATGAATTTTAAAA ATGAAATATGTATTCCTCTAAAACCCAAACTTTTATCTTTCCATTGGTATCTTTGAATTTTAAGACACT TTTCTTCAAATTACAAAACACTAAAACTCACTCCTAAACTTCACTTTGAGAAACTTTTTTAACCAATTA TAAAAATAAAACCATCCCCATGTGTTTCTTGCATATTCTAAAAACAGAAGTGTTAAAAATACACCACAC AGGCTGGGCAGAGTGGCTCACGCCTGTAACTCCAGCACTTTGGGAGGCCAAGATGGGCGGATCAGGACA GAGAATGAGGCCATCCTGGCCAACATGGTGAAACCCAATCTCTACTAAAAGTACAAAAATTAGCTGAGC GTGGTGGCACGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAG GTGGAGGCTGCAGTGAGCCAAGATCGCACCACCACGCTCCAGCCTGGTGACAGAGCGAGACTCCGTCTC AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACACCATACAGCTTTCATGTCATTGAAAGTTCTTA CTGGGTCAAAGCCTTAAGGCTAGAACTACCATTTTCTTGTCAACAGAATTCAGGCTATTCCAGTTTGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_016341.4 |
Synonyms | NPHS3; PLCE; PPLC |
Summary | This gene encodes a phospholipase enzyme that catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate to generate two second messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). These second messengers subsequently regulate various processes affecting cell growth, differentiation, and gene expression. This enzyme is regulated by small monomeric GTPases of the Ras and Rho families and by heterotrimeric G proteins. In addition to its phospholipase C catalytic activity, this enzyme has an N-terminal domain with guanine nucleotide exchange (GEF) activity. Mutations in this gene cause early-onset nephrotic syndrome; characterized by proteinuria, edema, and diffuse mesangial sclerosis or focal and segmental glomerulosclerosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009] |
Locus ID | 51196 |
MW | 77.6 |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Functional role of PLCE1 intronic insertion variant associated with susceptibility to esophageal squamous cell carcinoma.
,null,
Carcinogenesis
,PubMed ID 29106514
[PLCE1]
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