DPP1 (CTSC) (NM_001814) Human 3' UTR Clone

Specifications

Product Data
Product Name	DPP1 (CTSC) (NM_001814) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CPPI; DPP-I; DPP1; DPPI; HMS; JP; JPD; PALS; PDON1; PLS
ACCN	NM_001814
Insert Size	444 bp
Sequence Data	Insert Sequence (showhide) >SC205824 3’UTR clone of NM_001814 The sequence shown below is from the reference sequence of NM_001814. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTGGCAGCCACACCAATTCCTAAATTGTAGGGTATGCCTTCCAGTATTTCATAATGATCTGCATCAGTT GTAAAGGGGAATTGGTATATTCACAGACTGTAGACTTTCAGCAGCAATCTCAGAAGCTTACAAATAGAT TTCCATGAAGATATTTGTCTTCAGAATTAAAACTGCCCTTAATTTTAATATACCTTTCAATCGGCCACT GGCCATTTTTTTCTAAGTATTCAATTAAGTGGGAATTTTCTGGAAGATGGTCAGCTATGAAGTAATAGA GTTTGCTTAATCATTTGTAATTCAAACATGCTATATTTTTTAAAATCAATGTGAAAACATAGACTTATT TTTAAATTGTACCAATCACAAGAAAATAATGGCAATAATTATCAAAACTTTTAAAATAGATGCTCATAT TTTTAAAATAAAGTTTTAAAAATAACTGCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001814.6
Synonyms	CPPI; DPP-I; DPP1; DPPI; HMS; JP; JPD; PALS; PDON1; PLS
Summary	This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. [provided by RefSeq, Nov 2015]
Locus ID	1075
MW	17

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