Argininosuccinate Lyase (ASL) (NM_000048) Human 3' UTR Clone

Specifications

Product Data
Product Name	Argininosuccinate Lyase (ASL) (NM_000048) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ASAL
ACCN	NM_000048
Insert Size	694 bp
Sequence Data	Insert Sequence (showhide) >SC205812 3’UTR clone of NM_000048 The sequence shown below is from the reference sequence of NM_000048. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGGGCGCTACTGCAGGCACAGCAGGCCTAGGTCCTCCCACACCTGCCCCCTAATAAAGTGGGCGCGAGA GGAGGCTGCTGTGTGTTTCCTGCCCCAGCCTGGCTCCCTCGTTGCTGGGCTTTCGGGGCTGGCCAGTGG GGACAGTCAGGGACTGGAGAGGCAGGGCAGGGTGGCCTGTAATCCCAGCACTTTGGAAGGGCAAGGTGC GAGGATGCTTGAGGCCAGGAGTTTGACACAGCCTGGGCAACACAGGGAGACCCCCATCTCTACTCAATA ATAAAACAAATAGCCTGGCGTGGTGGCCCATGCATATAGTCCCAGCTACTTGTAAGGCTGAGGTGAGAG GACACTTGTGCCCAGGAGTGGAGGCTGCAGTGAGCTATGATCACGCCACTGCATTCCAGCCTGGATAAC AGAGTGAGAACCTATCTCTAAAAATAAATAAATAAACGAAAAATAAATGGAAGCGGAGAAAACTGGGCA AGGGCAATGAGAGTCGTAGACGGGAAGGGAAGAGGGGGCTCCCATCATAGCCTCTGCTCTGTCCAGGCC CCATCCCCTTCAGACAGGGTATCACAGTGACCTCCTAGGCCAGGAGCGATGGCTCACGCCTGTAATCCT AGCATTTTGGGAGGCCTGGGCAACAGGAAGACTCCAACTACCATATTAAAAAAAACATGAATGAAAGCA AAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000048.4
Synonyms	ASAL
Summary	This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Locus ID	435
MW	25.1

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