Chk1 (CHEK1) (NM_001274) Human 3' UTR Clone

Specifications

Product Data
Product Name	Chk1 (CHEK1) (NM_001274) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CHK1
ACCN	NM_001274
Insert Size	1876 bp
Sequence Data	Insert Sequence (showhide) >SC205740 3’UTR clone of NM_001274 The sequence shown below is from the reference sequence of NM_001274. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGCCAGAAGATTTGGCTTCCTGCCACATGATCGGACCATCGGCTCTGGGGAATCCTGGTGAATATAGTG CTGCTATGTTGACATTATTCTTCCTAGAGAAGATTATCCTGTCCTGCAAACTGCAAATAGTAGTTCCTG AAGTGTTCACTTCCCTGTTTATCCAAACATCTTCCAATTTATTTTGTTTGTTCGGCATACAAATAATAC CTATATCTTAATTGTAAGCAAAACTTTGGGGAAAGGATGAATAGAATTCATTTGATTATTTCTTCATGT GTGTTTAGTATCTGAATTTGAAACTCATCTGGTGGAAACCAAGTTTCAGGGGACATGAGTTTTCCAGCT TTTATACACACGTATCTCATTTTTATCAAAACATTTTGTTTAATTCAAAAAGTACATATTCCATGTTGA TTTAATTCTAAGATGAACCAATAAAGACATAATTCTTGTGACTTTTGGACAGTAGATTTATCAGTCTGT GAAGCGAAGCCAGCTTCAAAACATATCCCCAAGATTTGTACTTATATTTTCAAAAGGGCCTGGCCAGTT ATATAAACCTGTTTTTGAATTATAATGATTAATTAAAATTGCAAGTAGGTGTTTTTTCCAGTGTAGTTA GTAAAATACTTGTATTTTACAGTGTTGCATAAACTCTAGTGCTTAACTAACTTTACTCTAAAAATTACT GTTGAACATCTTAAATATTTTTCTATATTTTCTACTTTCATAGCCATATTTTAACCTTTTCAACTTACT GGTGACCAAGCTTTTAGGTGATAAAGAATAAAAGAGGGAAGGGAAGAGTAAGGAAGCTATAAGAAAAAT AGATCTGATTCTTTGTTCCTTTACCTGTTAGACTTACAAAAAGTTTGTTTTTCTAATAAAATTTGTATC AACTTTGGGGCATATTAGGTTGAGGCCTTGGCTCCTGCCTGTAGTCCCAGCTACTTAGGAGGCTGAGAG AGGAGGATCGCGTGAACCTGGAAGTTTGAGGCTGTAGTGAGCTATGATTGCACCAGTGCACTCCAGCTT GGATGACAGAGTAAGACCCTACCTCTAATAAAAATTTTTAAAATTGTAAAACATTATAAAATTAATCAG TTATTTTAATCTGAAGCCAAGAACATGTAGAATGTTATGATTAGAGTTTATCACATATTAATGTATACT GGCAAATTGTGTTACTGGAGTATACCCATAGGAGGAATAAATTCAAACCTGTTTTATTTATTTGAACCT ATTTACGGTATGCTTAAGAATTGAATCAGTATAAATTCTCAAATATGGGAGAAATTTTGTTCTTGAGAA TTATCTGAGTCATTAATATTTTTCAAAAACAGCTCTCACTGACTTGAACCTCTTCTGTAAGCTCTAACC TTTTACCTGCTTTACATTTCCACTTGAATGTCTAGTAGGCATCTCTTGACCAAAAACAGCTTTTGATTC CTGTTCTCCAACCTGTTCCTCTCCTAGTTTTCTCCATCTCAGAAATGTTACTTCCTCTGCAAAGTCTTT CCCTGACTTATCTAAAATAATAACCTCCTCTGTTTGCTGTGGGAATTTGTATAGAATGGTGGGAAAATT TCAAGTTTCATATTTGGATTAGCTCTGACATTTATTTATCTGAACACTGGTAATTGCCTCAGTAAAGAC ACTGATAATAAGTACCTTTTAGAGTTATTTTAATCTTTAATGCTTTAATGTGTAGGAAGAGTATAGTGT CCTGTTTTGCACAGAAAGGCATTCTGTAAATAATAAGTTGCCTTAATTTTCCTGTAATGTTCATTATAT TGTTGTGGGAAGGTATTTACTCCTATTATTAAAAATAAAAATGTGTAAAATTTACTACCTGAAAAAAAA AAAAAAAAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001274.5
Synonyms	CHK1
Summary	The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011]
Locus ID	1111
MW	72.3

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