FE65 (APBB1) (NM_145689) Human 3' UTR Clone

Specifications

Product Data
Product Name	FE65 (APBB1) (NM_145689) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	FE65; MGC:9072; RIR
ACCN	NM_145689
Insert Size	439 bp
Sequence Data	Insert Sequence (showhide) >SC205730 3’UTR clone of NM_145689 The sequence shown below is from the reference sequence of NM_145689. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCCAAACGGCTGGGGGCCCATACCCCATGAAGAAGCCCCCACCTTCCCTCCACCTGCTTGTGTTGGGCC CCAGGGAACTAAAGGGTGTGGGTCAGGGAGGGGTCTAGAGGCTATTCCTAGGCCTCAGGCCTCCCAAAT ATGCCCCTCCCCAGTAGCTACGGTTCCCTGCCTAGGAGCTGGGGAGGGAGAGATCTAATCCCTTCAAGG AAGTGATAACACTGGAGTGGTAACAAGAGGAGCAGGAAGCAAGGCCAGCCCTGGTTCTCCATCCCCATG TGTTTCAGGTGGAACAGGAGGAACTGGTCCAGGCCAGGCCTCATCCTCCTGGACCCAGCAGGGGCAGAA GGAGGAAGGGACTGGTCCAGGCATGGGTCCCTTCCCCCTGCTCCATGGGCACCTCTGCTGTATTGATAT CACTAATAAAGTCTGTCTGCACTGC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_145689.3
Synonyms	FE65; MGC:9072; RIR
Summary	The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]
Locus ID	322
MW	16.5

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