PPP4C (NM_002720) Human 3' UTR Clone
CAT#: SC205397
3' UTR clone of protein phosphatase 4 (formerly X) catalytic subunit (PPP4C) for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
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经常一起买 (2)
Specifications
Product Data | |
Product Name | PPP4C (NM_002720) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | PP-X; PP4; PP4C; PPH3; PPP4; PPX |
ACCN | NM_002720 |
Insert Size | 344 bp |
Sequence Data |
>SC205397 3’UTR clone of NM_002720
The sequence shown below is from the reference sequence of NM_002720. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGAAGCCCGTGGCCGACTACTTCCTGTGACCCCGCCCGGCCCCTGCCCCCTCCAACCCTTCTGGCCCT CGCACCACTGTGACTCTGCCATCTTCCTCAGACGGAGGCTGGGCGTGGGGGGGGCTGTCCTGGCTCTGC TGTCCCCCAAGAGGGTGCTTCGAGGGTGAGGACTTCTCTGGAGAGGCCTGGAGACCTAGCTCCATGTTC CTCCTCCTCTCTCCCCACTTGAACCATGAAGTTTCCAATAATTTTTTTTTCTTTTTTTCCTTCTTTTTT CTGTTTGTTTTTAGATAAAAATTTTGAGAAAAAAAATGAAAAAATTCTAATAAAAGAAGAAAAATGGT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_002720.3 |
Synonyms | PP-X; PP4; PP4C; PPH3; PPP4; PPX |
Summary | Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin.[UniProtKB/Swiss-Prot Function] |
Locus ID | 5531 |
MW | 13.1 |
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