ABCA4 (NM_000350) Human 3' UTR Clone

Specifications

Product Data
Product Name	ABCA4 (NM_000350) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ABC10; ABCR; ARMD2; CORD3; FFM; RMP; RP19; STGD; STGD1
ACCN	NM_000350
Insert Size	433 bp
Sequence Data	Insert Sequence (showhide) >SC205376 3’UTR clone of NM_000350 The sequence shown below is from the reference sequence of NM_000350. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCTGGAGCCAGTCGACAAGCCCAGGACTGATCTTTCACACCGCTCGTTCCTGCAGCCAGAAAGGAACTC TGGGCAGCTGGAGGCGCAGGAGCCTGTGCCCATATGGTCATCCAAATGGACTGGCCAGCGTAAATGACC CCACTGCAGCAGAAAACAAACACACGAGGAGCATGCAGCGAATTCAGAAAGAGGTCTTTCAGAAGGAAA CCGAAACTGACTTGCTCACCTGGAACACCTGATGGTGAAACCAAACAAATACAAAATCCTTCTCCAGAC CCCAGAACTAGAAACCCCGGGCCATCCCACTAGCAGCTTTGGCCTCCATATTGCTCTCATTTCAAGCAG ATCTGCTTTTCTGCATGTTTGTCTGTGTGTCTGCGTTGTGTGTGATTTTCATGGAAAAATAAAATGCAA ATGCACTCATCACAAACTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000350.3
Synonyms	ABC10; ABCR; ARMD2; CORD3; FFM; RMP; RP19; STGD; STGD1
Summary	The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, and the gene product mediates transport of an essental molecule, all-trans-retinal aldehyde (atRAL), across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2. [provided by RefSeq, Sep 2019]
Locus ID	24
MW	16.1

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