ASXL1 (NM_001164603) Human 3' UTR Clone

Specifications

Product Data
Product Name	ASXL1 (NM_001164603) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BOPS; MDS
ACCN	NM_001164603
Insert Size	424 bp
Sequence Data	Insert Sequence (showhide) >SC205289 3’UTR clone of NM_001164603 The sequence shown below is from the reference sequence of NM_001164603. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGAATCAGCCTTTTCACGCTCAAGGTGTGAGCCACTGCACCAGGCCCCTTCATCTTAATTTTAATATAT CTTTGAATAAACACCATTGTATGAACCTGCTGTAAGCTTGGGAGTGGTCTGTTAGTCTACAGCTTGTGT CTGAGATGTGCTAATTGAATATTTGCTCAGTACCTCATCTTAACTGCCTTTGGCTTTATGTTGCTTATC CTTCATAGTATCTTGTTCATTGGCCTTTTACATCCATAGGCATCACTTCTCTGATATTCGTTGTGCTCT TTTAATGGATTAATGGTTTGCTTGGTTGGTTCCTCTAGTTAGACTGTAAACTCCTTGAGAGCAGAGTCT GTATTTTATTAATTACCCACAGTACTAGGTACATAGTTGCCTTCAATAAATATATATTTAATGAAAAAA AAAAAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001164603.1
Synonyms	BOPS; MDS
Summary	This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Locus ID	171023
MW	15.5

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