Factor D (CFD) (NM_001928) Human 3' UTR Clone

Specifications

Product Data
Product Name	Factor D (CFD) (NM_001928) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ADIPSIN; ADN; DF; PFD
ACCN	NM_001928
Insert Size	381 bp
Sequence Data	Insert Sequence (showhide) >SC205200 3' UTR clone of NM_001928 The sequence shown below is from the reference sequence of NM_001928. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC CTGGATCGACAGCGTCCTGGCCTAGGGTGCCGGGGCCTGAAGGTCAGGGTCACCCAAGCAACAAAGTCCC GAGCAATGAAGTCATCCACTCCTGCATCTGGTTGGTCTTTATTGAGCACCTACTATATGCAGAAGGGGAG GCCGAGGTGGGAGGATCATTGGATCTCAGGAGTTCGAGATCAGCATGGGCCACGTAGCGCGACTCCATCT CTACAAATAAATAAAAAATTAGCTGGGCAATTGGCGGGCATGGAGGTGGGTGCTTGTAGTTCCAGCTACT CAGGAGGCTGAGGTGGGAGGATGACTTGAACGCAGGAGGCTGAGGCTGCAGTGAGTTGTGATTGCACCAC TGCCCTCCAGCCTGGGCAACAGAGTGAAACC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001928.2
Synonyms	ADIPSIN; ADN; DF; PFD
Summary	This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015]
Locus ID	1675

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