Cytochrome P450 Reductase (POR) (NM_000941) Human 3' UTR Clone

Specifications

Product Data
Product Name	Cytochrome P450 Reductase (POR) (NM_000941) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CPR; CYPOR; P450R
ACCN	NM_000941
Insert Size	404 bp
Sequence Data	Insert Sequence (showhide) >SC205168 3’UTR clone of NM_000941 The sequence shown below is from the reference sequence of NM_000941. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGCCGCTACTCCCTGGACGTGTGGAGCTAGGGGCCTGCCTGCCCCACCCACCCCACAGACTCCGGCCTG TAATCAGCTCTCCTGGCTCCCTCCCGTAGTCTCCTGGGTGTGTTTGGCTTGGCCTTGGCATGGGCGCAG GCCCAGTGACAAAGACTCCTCTGGGCCTGGGGTGCATCCTCCTCAGCCCCCAGGCCAGGTGAGGTCCAC CGGCCCCTGGCAGCACAGCCCAGGGCCTGCATGGGGGCACCGGGCTCCATGCCTCTGGAGGCCTCTGGC CCTCGGTGGCTGCACAGAAGGGCTCTTTCTCTCTGCTGAGCTGGGCCCAGCCCCTCCACGTGATTTCCA GTGAGTGTAAATAATTTTAAATAACCTCTGGCCCTTGGAATAAAGTTCTGTTTTCTGTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000941.3
Synonyms	CPR; CYPOR; P450R
Summary	This gene encodes an endoplasmic reticulum membrane oxidoreductase that is essential for multiple metabolic processes, including reactions catalyzed by cytochrome P450 proteins for metabolism of steroid hormones, drugs and xenobiotics. The encoded protein has a flavin adenine dinucleotide (FAD)-binding domain and a flavodoxin-like domain which bind two cofactors, FAD and FMN, that allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene cause a complex set of disorders, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome, that resemble those caused by defects in steroid metabolizing enzymes such as aromatase, 21-hydroxylase, and 17 alpha-hydroxylase. [provided by RefSeq, Aug 2020]
Locus ID	5447
MW	14.2

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