p18 INK4c (CDKN2C) (NM_001262) Human 3' UTR Clone

Specifications

Product Data
Product Name	p18 INK4c (CDKN2C) (NM_001262) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	INK4C; p18; p18-INK4C
ACCN	NM_001262
Insert Size	394 bp
Sequence Data	Insert Sequence (showhide) >SC205117 3’UTR clone of NM_001262 The sequence shown below is from the reference sequence of NM_001262. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGGGCTGGGGGAGCCACAAATCTTCAATAAACGTGGGGAGGGCTCCCCCACGTTGCCTCTACTTTATCA ATTAACTGAGTAGCTCTCCTGACTTTTAATGTCATTTGTTAAAATACAGTTCTGTCATATGTTAAGCAG CTAAATTTTCTGAAACTGCATAAGTGAAAATCTTACAACAGGCTTATGAATATATTTAAGCAACATCTT TTTAACCTGCAAAATCTGTTCTAACATGTAATTGCAGATAACTTTGACTTTCTTCTGAATATTTTATCT TTCCTTGGCTTTTCCCTTGCTTCCCCTTTTGCCAATCTCAACACCCAAGTTGAAGACTTTGTTTTTAAA ATGGTTTGTCCTGATGCTTTTGTCTAATTAAAACACTTTCAAAACAGGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001262.3
Synonyms	INK4C; p18; p18-INK4C
Summary	The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]
Locus ID	1031
MW	14.9

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