TCPTP (PTPN2) (NM_080423) Human 3' UTR Clone

Specifications

Product Data
Product Name	TCPTP (PTPN2) (NM_080423) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	PTN2; PTPT; TC-PTP; TCELLPTP; TCPTP
ACCN	NM_080423
Insert Size	375 bp
Sequence Data	Insert Sequence (showhide) >SC204940 3’UTR clone of NM_080423 The sequence shown below is from the reference sequence of NM_080423. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGTGAGAGGCCAAGATTGACAGACACCTAATATTCATGACTTGAGAATATTCTGCAGCTATAAATTTTG AACCATTGATGTGCAAAGCAAGACCTGAAGCCCACTCCGGAAACTAAAGTGAGGCTCGCTAACCCTCTA GATTGCCTCACAGTTGTTTGTTTACAAAGTAAACTTTACATCCAGGGGATGAAGAGCACCCACCAGCAG AAGACTTTGCAGAACCTTTAATTGGATGTGTTAAGTGTTTTTAATGAGTGTATGAAATGTAGAAAGATG TACAAGAAATAAATTAGGGGAGATTACTTTGTATTGTACTGCCATTCCTACTGTATTTTTATACTTTTT GGCAGCATTAAATATTTTTGTTAAATAGTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_080423.3
Synonyms	PTN2; PTPT; TC-PTP; TCELLPTP; TCPTP
Summary	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011]
Locus ID	5771
MW	14.7

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