BYSL (NM_004053) Human 3' UTR Clone

Specifications

Product Data
Product Name	BYSL (NM_004053) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BYSTIN; Enp1
ACCN	NM_004053
Insert Size	370 bp
Sequence Data	Insert Sequence (showhide) >SC204765 3’UTR clone of NM_004053 The sequence shown below is from the reference sequence of NM_004053. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTGGAAGATGTTCCCATCACCGTGGAGTGAGGAAAACAGTCAGCTGTCCTGGCCAAAGGGGTTTGGAAG GACACCAAGACCCCCGTTGGTGACTGAAGATGACACTGAGCTTTAATGGCTGAAGACCCAGATCAGGGC AGTGACAGATCACAGGGACATCTGTGGCTCCCAGTCCAGGACAGGAAGGACTGAGGGTCTGGCTGGTTC CCTCTTCCATTCTAGGCCCTTATCCCTGTTTAGTTCTGAGAGCCAACTTGAGATACCATATGCTAGCAT TCCCAGTCCCCAGCTGGGGCTTGGTGTGAGTACTTTTTCTATGGCTATTGTGTCAGGTCACTGTGGATA AAGGCAAAGACAGATATTTATTGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004053.4
Synonyms	BYSTIN; Enp1
Summary	Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation. Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregnancy. Both proteins were localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi. [provided by RefSeq, Jul 2008]
Locus ID	705
MW	13.8

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