NXF1 (NM_006362) Human 3' UTR Clone

Specifications

Product Data
Product Name	NXF1 (NM_006362) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MEX67; TAP
ACCN	NM_006362
Insert Size	376 bp
Sequence Data	Insert Sequence (showhide) >SC204700 3’UTR clone of NM_006362 The sequence shown below is from the reference sequence of NM_006362. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAGATCCCAGAAGTGGCATTCATGAAGTGATCGTAGTCATGCCTCAGAAGCAGTCCCCCCTGTAAATAG TCCTTGGATATTACCGTCTGGTTGTCGTCTGTCATCTCCTCCTGTCTGGCCCGAGGCCGCCCCGTGACT GTGACCGAGGGAGGGAGGGCTGCCTGATCCCTCTCCTCGCCTGCCTTCTGGAAGACTTCAGAAGATTGA GCCTCACTGGTGCCAGGAAGCCAAAGCTTACTTTGTAGAACTGACACTAAACTACCCGAAGGACTTAGG TGCTTTGTGTACTTAACCCCAGGACCTCCTTACTTTTTAATATAAAGAGTGATGTTGTATTTCGTGTTC TGCACTTTTTAATATAAAGAGTGATGTTGTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006362.5
Synonyms	MEX67; TAP
Summary	This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Locus ID	10482
MW	13.9

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