REA (PHB2) (NM_001144831) Human 3' UTR Clone

Specifications

Product Data
Product Name	REA (PHB2) (NM_001144831) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BAP; Bap37; BCAP37; hBAP; p22; PNAS-141; REA
ACCN	NM_001144831
Insert Size	388 bp
Sequence Data	Insert Sequence (showhide) >SC204660 3’UTR clone of NM_001144831 The sequence shown below is from the reference sequence of NM_001144831. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGTGACAGCCTCATCAAGGGTAAGAAATGAGCCTAGTCACCAAGAACTCCACCCCCAGAGGAAGTGGAT CTGCTTCTCCAGTTTTTGAGGAGCCAGCCAGGGGTCCAGCACAGCCCTACCCCGCCCCAGTATCATGCG ATGGTCCCCCACACCGGTTCCCTGAACCCCTCTTGGATTAAGGAAGACTGAAGACTAGCCCCTTTTCTG GGGAATTACTTTCCTCCTCCCTGTGTTAACTGGGGCTGTTGGGGACAGTGCGTGATTTCTCAGTGATTT CCTACAGTGTTGTTCCCTCCCTCAAGGCTGGGAGGAGATAAACACCAACCCAGGAATTCTCAATAAATT TTTATTACTTAACCTGAAGTCAAGGCTTCACGTGTTCATGAAC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001144831.2
Synonyms	BAP; Bap37; BCAP37; hBAP; p22; PNAS-141; REA
Summary	Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. In mitochondria, regulates cytochrome-c oxidase assembly (COX) and mitochondrial respiration. Binding to sphingoid 1-phosphate (SPP) modulates its regulator activity (PubMed:20959514).[UniProtKB/Swiss-Prot Function]
Locus ID	11331
MW	14.5

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