Mps1 (TTK) (NM_003318) Human 3' UTR Clone

Specifications

Product Data
Product Name	Mps1 (TTK) (NM_003318) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CT96; ESK; MPH1; MPS1; MPS1L1; PYT
ACCN	NM_003318
Insert Size	355 bp
Sequence Data	Insert Sequence (showhide) >SC204305 3’UTR clone of NM_003318 The sequence shown below is from the reference sequence of NM_003318. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACTTTTGAAAAAAAAAGGGGAAAAAAATGATTTGCAGTTATTCGTAATGTCAGATACCACCTATAAAAT ATATTGGACTGTTATACTCTTGAATCCCTGTGGAAATCTACATTTGAAGACAACATCACTCTGAAGTGT TATCAGCAAAAAAAATTCAGTAGATTATCTTTAAAAGAAAACTGTAAAAATAGCAACCACTTATGGCAC TGTATATATTGTAGACTTGTTTTCTCTGTTTTATGCTCTTGTGTAATCTACTTGACATCATTTTACTCT TGGAATAGTGGGTGGATAGCAAGTATATTCTAAAAAACTTTGTAAATAAAGTTTTGTGGCTAAAATGAC ACTAACATTT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003318.5
Synonyms	CT96; ESK; MPH1; MPS1; MPS1L1; PYT
Summary	This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
Locus ID	7272
MW	14.1

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