SLC22A17 (NM_016609) Human 3' UTR Clone

Specifications

Product Data
Product Name	SLC22A17 (NM_016609) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	24p3R; BOCT; BOIT; hBOIT; NGALR; NGALR2; NGALR3
ACCN	NM_016609
Insert Size	360 bp
Sequence Data	Insert Sequence (showhide) >SC204185 3’UTR clone of NM_016609 The sequence shown below is from the reference sequence of NM_016609. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTGCTTGCCACCCCCAACCCTGCCCTCTGAGCGGCCTCTGAGTACCCTGGCGGGAGGCTGGCCCACACA GAAAGGTGGCAAGAAGATCGGGAAGACTGAGTAGGGAAGGCAGGGCTGCCCAGAAGTCTCAGAGGCACC TCACGCCAGCCATCGCGGAGAGCTCAGAGGGCCGTCCCCACCCTGCCTCCTCCCTGCTGCTTTGCATTC ACTTCCTTGGCCAGAGTCAGGGGACAGGGAGAGAGCTCCACACTGTAACCACTGGGTCTGGGCTCCATC CTGCGCCCAAAGACATCCACCCAGACCTCATTATTTCTTGCTCTATCATTCTGTTTCAATAAAGACATT TGGAATAAACGAGCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_016609.7
Synonyms	24p3R; BOCT; BOIT; hBOIT; NGALR; NGALR2; NGALR3
Summary	Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis (By similarity).[UniProtKB/Swiss-Prot Function]
Locus ID	51310
MW	13.1

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