BMP4 (NM_130850) Human 3' UTR Clone

Specifications

Product Data
Product Name	BMP4 (NM_130850) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BMP2B; BMP2B1; MCOPS6; OFC11; ZYME
ACCN	NM_130850
Insert Size	326 bp
Sequence Data	Insert Sequence (showhide) >SC204083 3’UTR clone of NM_130850 The sequence shown below is from the reference sequence of NM_130850. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATGGTAGTAGAGGGATGTGGGTGCCGCTGAGATCAGGCAGTCCTTGAGGATAGACAGATATACACACCA CACACACACACCACATACACCACACACACACGTTCCCATCCACTCACCCACACACTACACAGACTGCTT CCTTATAGCTGGACTTTTATTTAAAAAAAAAAAAAAAAAAGGAAAAAATCCCTAAACATTCACCTTGAC CTTATTTATGACTTTACGTGCAAATGTTTTGACCATATTGATCATATATTTTGACAAAATATATTTATA ACTACGTATTAAAAGAAAAAAATAAAATGAGTCATTATTTTAAAGGTAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_130850.5
Synonyms	BMP2B; BMP2B1; MCOPS6; OFC11; ZYME
Summary	This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016]
Locus ID	652
MW	12.9

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