emopamil binding protein (EBP) (NM_006579) Human 3' UTR Clone

Specifications

Product Data
Product Name	emopamil binding protein (EBP) (NM_006579) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CDPX2; CHO2; CPX; CPXD; MEND
ACCN	NM_006579
Insert Size	289 bp
Sequence Data	Insert Sequence (showhide) >SC203820 3’UTR clone of NM_006579 The sequence shown below is from the reference sequence of NM_006579. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCCACAAAAGCCAAGAGCAAGAAGAACTGAGGAGTGGTGGACCAGGCTCGAACACTGGCCGAGGAGGAG CTCTCTGCCTGCCAGAAGAGTCTAGTCCTGCTCCCACAGTTTGGAGGGACAAAGCTAATTGATCTGTCA CACTCAGGCTCATGGGCAGGCACAAGAAGGGGAATAAAGGGGCTGTGTGAAGGCACTGCTGGGAGCCAT TAGAACACAGATACAAGAGAAGCCAGGAGGTCTATGATGGTGACGATTTTTAAAATCAGGAAATAAAAG ATCTTGACTCTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006579.3
Synonyms	CDPX2; CHO2; CPX; CPXD; MEND
Summary	The protein encoded by this gene is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23%) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2; also known as Conradi-Hunermann syndrome). [provided by RefSeq, Jul 2008]
Locus ID	10682
MW	10.5

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