CD8B (NM_172213) Human 3' UTR Clone

Specifications

Product Data
Product Name	CD8B (NM_172213) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CD8B1; LEU2; LY3; LYT3; P37
ACCN	NM_172213
Insert Size	268 bp
Sequence Data	Insert Sequence (showhide) >SC203631 3’UTR clone of NM_172213 The sequence shown below is from the reference sequence of NM_172213. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTGCTTAACCCATGGATCCTGAAAACATAGGCAAGAAGCACAGGTCCTGATGAGTGGATCTTTACTACT TTTACCAGATTCCTCCCTCGCTCAGAGGGATCCTCCCACACACCCAGCAGAGACTTCTCTGCCACCATC AACCCCCCAAGTCATAGGGGGCTCAAGTTCTGCCCTGGTGAGCTGTGGCCCCCATCCTTGTGAACCCCA AAGTGTCCCCCTTGTGGAACCAAATGTATCCATCTTGAATAAATTTGCCCAAAATCCTAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_172213.5
Synonyms	CD8B1; LEU2; LY3; LYT3; P37
Summary	The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010]
Locus ID	926
MW	9.8

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