CCR4 NOT transcription complex subunit 3 (CNOT3) (NM_014516) Human 3' UTR Clone

Specifications

Product Data
Product Name	CCR4 NOT transcription complex subunit 3 (CNOT3) (NM_014516) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	IDDSADF; LENG2; NOT3; NOT3H
ACCN	NM_014516
Insert Size	304 bp
Sequence Data	Insert Sequence (showhide) >SC203623 3’UTR clone of NM_014516 The sequence shown below is from the reference sequence of NM_014516. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGCTACCTGGAGGACCGGGACCTCCAGTGACACCGGCCCCTCCCTCTACCCACCCCCTTCCCCCGCATG CTGATCCCCCTGCCCAGGTGAGGGCCCTGCCCTGGAAGACTGGAGGGAGGCCCCAAGCCACGGGGCATC CCCCTCTCCCAGGAAGCAGGGAGGGGGCCGGGAGGTTTTCCTCTCAGCCCCACCCTGGGGGCCCGGGGG CGAGGGCTGCCCCCTCCTCCCCTCCCCAGTGAGGGACATTTTTTGGTAAACCTATTTTCATTTTGGAAA ATATTTATGAATAAATAGTTTTATATGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_014516.4
Synonyms	IDDSADF; LENG2; NOT3; NOT3H
Summary	Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may involve histone deacetylases. Involved in the maintenance of embryonic stem (ES) cell identity.[UniProtKB/Swiss-Prot Function]
Locus ID	4849
MW	11.3

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