HNMT (NM_001024075) Human 3' UTR Clone

Specifications

Product Data
Product Name	HNMT (NM_001024075) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HMT; HNMT-S1; HNMT-S2; MRT51
ACCN	NM_001024075
Insert Size	248 bp
Sequence Data	Insert Sequence (showhide) >SC203453 3’UTR clone of NM_001024075 The sequence shown below is from the reference sequence of NM_001024075. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCATTCCTAGTTTCCTTCATCCTCTTTTAAGTGTCATCTTTTCCATGAAGCCTACTAGATCACACAGTT GAAAATTGCAAAGTCTTCACACCGCAGCTTCCCCTTTCTTTGTTGCTTTGGTTTTCTCCGTGGGACTTC CCACCATCCGTAAAATTAGGTGTTTTTGCCTGTTTTATTCACTGCTACGTCTCCAATGGTTAGAACCTG ACATTTAGTGGGTGCTCAATAATATTTGTTGAAGTAATGTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001024075.3
Synonyms	HMT; HNMT-S1; HNMT-S2; MRT51
Summary	In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
Locus ID	3176
MW	9.2

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