Thyroid Peroxidase (TPO) (NM_175721) Human 3' UTR Clone

Specifications

Product Data
Product Name	Thyroid Peroxidase (TPO) (NM_175721) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MSA; TDH2A; TPX
ACCN	NM_175721
Insert Size	289 bp
Sequence Data	Insert Sequence (showhide) >SC203237 3’UTR clone of NM_175721 The sequence shown below is from the reference sequence of NM_175721. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GATACTCACAGGCTGCCGAGAGCCCTCTGAGGGCAAAGTGGCAGGACACTGCAGAACAGCTTCATGTTC CCAAAATCACCGTACGACTCTTTTCCAAACACAGGCAAATCCGAAATCAGCAGGACGACTGTTTTCCCA ACACGGGTAAATCTAGTACCATGTCGTAGTTACTCTCAGGCATGGATGAATAAATGTTATAGCTGCATT TGTCTGGCCTTTTCTTGTAAACATTGCCTGATTTGTTCCTTCTGGGGCTTTGCCATTAAAATGTATTTA CAGATTAAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_175721.3
Synonyms	MSA; TDH2A; TPX
Summary	This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
Locus ID	7173
MW	11.1

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