DUSP12 (NM_007240) Human 3' UTR Clone

Specifications

Product Data
Product Name	DUSP12 (NM_007240) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	DUSP1; YVH1
ACCN	NM_007240
Insert Size	321 bp
Sequence Data	Insert Sequence (showhide) >SC202852 3’UTR clone of NM_007240 The sequence shown below is from the reference sequence of NM_007240. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTTTTGGGATCACAAACAGGAAAAATATGAACATGATATTTTATAGCTTGGGAAGAAACTTGCAGATGA TATGTGCTGCCTTTGCTTCTTATCATTCATGGCAGATTGTTTGTGCTTTCAACATTTCATTTGAAATGG GAGAAGATAAAATCACTTGATGTAACCTGGAAACTATGCTTTACATGGCAATCAAAGCCTTTTGATCAT GTACATTTTATTTGATATTAAAATCTTTTATAACCAGATACTGTCTGTGTTTCATATATTTTTAAAAGT TTTGATTGTTGGAATGTTATATGATCTTAAGGTCTGTATAGACAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_007240.3
Synonyms	DUSP1; YVH1
Summary	The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq, Jul 2008]
Locus ID	11266
MW	12.8

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