SAFB (NM_002967) Human 3' UTR Clone
CAT#: SC202530
3' UTR clone of scaffold attachment factor B (SAFB) for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
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经常一起买 (2)
Specifications
Product Data | |
Product Name | SAFB (NM_002967) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | HAP; HET; SAB-B1; SAF-B; SAF-B1; SAFB1 |
ACCN | NM_002967 |
Insert Size | 217 bp |
Sequence Data |
>SC202530 3’UTR clone of NM_002967
The sequence shown below is from the reference sequence of NM_002967. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGCGATGCCCGCTTCACTCGCCGCTACTGAGTACTTGGAATCCTGTGTCCTGTCTCGTGGCAACAAGGC TATGTTCTGTTAGGAGTTACCTTAAACTGTGTAAAAATATTTTTTTTTAATCTGCTGCCATATTGTAGC TCAATACAATGTGAATTTGTTTTTCGTTTTGGGGTTTTTTTTTTTTGTAATAAATGTGTTTCCGTTCAC ATACCCTTTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_002967.4 |
Synonyms | HAP; HET; SAB-B1; SAF-B; SAF-B1; SAFB1 |
Summary | This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011] |
Locus ID | 6294 |
MW | 8.4 |
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