Complement factor 8 beta (C8B) (NM_000066) Human 3' UTR Clone

Specifications

Product Data
Product Name	Complement factor 8 beta (C8B) (NM_000066) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	C82
ACCN	NM_000066
Insert Size	227 bp
Sequence Data	Insert Sequence (showhide) >SC202395 3’UTR clone of NM_000066 The sequence shown below is from the reference sequence of NM_000066. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCTGCTTCAGAAACACTTGACTGCTCCTAGCAGATGATACAGCAGTGGGCTACATACAATGAGAGCCCT GAGCCCTCAAGAACTCATGCCAGCTCAGCCCTACACCAGTTTCCACCTGGAGTTCATGCAAGGGCAAAA GGCAGTGCCATGCAAGCTGTTTAAAATAAAGATGTTACCTTGTAAAATGCAAGTTGATTTAAATAAATA CTGAGTTAAAGGCTTAAGCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000066.4
Synonyms	C82
Summary	This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Locus ID	732
MW	8.3

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