Cyclin H (CCNH) (NM_001239) Human 3' UTR Clone

Specifications

Product Data
Product Name	Cyclin H (CCNH) (NM_001239) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CAK; CycH; p34; p37
ACCN	NM_001239
Insert Size	202 bp
Sequence Data	Insert Sequence (showhide) >SC202107 3’UTR clone of NM_001239 The sequence shown below is from the reference sequence of NM_001239. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACTGATGACGACCTGGTAGAATCTCTCTAACCATTTGAAGTTGATTTCTCAATGCTAACTAATCAAGAG AAGTAGGAAGCATATCAAACGTTTAACTTTATTTAAAAAGTATAATGTGAAAACATAAAATATATTAAA ACTTTTCTATTGTTTTCTTTCCCTTTCACAGTAACTTTATGTAAAATAAACCATCTTCAAAAGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001239.4
Synonyms	CAK; CycH; p34; p37
Summary	The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010]
Locus ID	902
MW	8

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