Ribonuclease H2, subunit A (RNASEH2A) (NM_006397) Human 3' UTR Clone

Specifications

Product Data
Product Name	Ribonuclease H2, subunit A (RNASEH2A) (NM_006397) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AGS4; JUNB; RNASEHI; RNHIA; RNHL; THSD8
ACCN	NM_006397
Insert Size	204 bp
Sequence Data	Insert Sequence (showhide) >SC202016 3’UTR clone of NM_006397 The sequence shown below is from the reference sequence of NM_006397. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGCGGCCTGGAGTCAGCAACCAGCCTCTAGCAGCTGCCTCTACGCGCTCTACCTGCTTCCCCAACCCAG ACATTAAAATTGTTTAAGGAGAACCACACGTAGGGGATGTACTTTTGGGACAGAAGCAAGGTGGGAGTG TGCTCTGCAGCCGGGTCCAGCTACTTCCTTTTGGAACCTTAAATAGAATGGGTGTTGGTTGATTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006397.3
Synonyms	AGS4; JUNB; RNASEHI; RNHIA; RNHL; THSD8
Summary	The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009]
Locus ID	10535
MW	7.5

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