53BP1 (TP53BP1) (NM_005657) Human 3' UTR Clone

Specifications

Product Data
Product Name	53BP1 (TP53BP1) (NM_005657) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	53BP1; p53BP1; p202; TDRD30
ACCN	NM_005657
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC201728 3’UTR clone of NM_005657 The sequence shown below is from the reference sequence of NM_005657. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAATATAAACACGATTATGTTTCTCACTAAAGATACTTGGTCTTACTGGTTTTATTCCCTGCTATCGTG GAGATTGTGTTTTAACCAGGTTTTAAATGTGTCTTGTGTGTAACTGGATTCCTTGCATGGATCTTGTAT ATAGTTTTATTTGCTGAACTTTTATGATAAAATAAATGTTGAATCTCTTTGGTTGTAGTAACTGGGATT TCTTCATCTGTTTTTTTGAGCTTAATCTCAGAACAAATGACAAGACATAGTACTTTCTCTGAGTCTTTC AACAGGCTTATTCACTTACGGAGGACAGCTGGCCAAGGAAATTGAAAAGTTAAGAGTGAACTTTATTCT GTGGCATCATTCCCAAAAGGTTATTCCAGGGTGTCTAAAATGCTATGCTTGCAGAAACTCAGTTTAAGG TAGGTGAAGGCCCAGATTAACAGTTGTGCCAAAAGTTGAGTGGAATTGGGCACAGCTCTGTTTCCTGAC AGTTAAAAAAGACCTCATGCTCTCTCTCTGAGCTGAGATCACAGCTCACCTGTGGGTACTCCCCAACTC TTAGAGCTAAAGGGAGAACGAAAGGACCAACTGCCATGAAGGGACAGTGACCATAAGCTTGATGGAATG ACCTTCCGTAAGATAAACATGGGAAGCACAAGTGAGAACACCTGGAAATGTTACACGTTCTAGTCAAAG ACCCAATATTATTATTATTATTATTGTCACAATAGCTGGAAGCAGTTCCTTCCCTTCCTCTGGCATCAC TGATCCCTGCATGGCTTCTCATTCTCTAAAGCAGGGGTCAACAAGGTTTTTTTCTGTAAAGGGTCAAAG AGTAAATATTTCAGGCTTTGTGGGCCATTTGATCCATCACAACTACTCGCCTTTGCTGTGAGGGCATGA AAGCAACCATAGACAATGAGTAAACAAATGGGCATGGCTGTGTTTCAGTAAAACTGTACAAAAACAGAC AGCAGGCCATAGTTTGCCAGCTCCTGCTCCAGAGACAGCAGTAGAAAGGGTGATCTTTAGTTGATAATA GCAGGGAATAAGTTGTCAGAGCTTCCCAGTGTGTGTAGAATATGTAGTGATGAAAACCAGATGCAGTGA CTATAACCTGATGCCAGAACACTGCATTCTTTTTCAGTTTGGAGGGCGTTGTTCAGTGAATATTTCTTT TTACTTACACTGATATGAATATTGATTACCAGTGATGGCTGGGCCATATTAAGATAACTTCAACCCCTA TGGTTTGTGTAAGATGGGTAATTGGGCCTGCAATCTTCAGTATTTAAAAATCTAACAACTTGATCTCAA TTTTTTCTTAAGGACCTTTTTCTTGGAGAATAATACTTTTTTTTTTTTTTTTTTTTTTTTTGAGACGGA ATTTCGCTCTTGTTGCCCGGGCTGGAATGCAATGGCACAATCTCAGCTCACTGCAGCGTCTGCTTCCCA GGTTCAAGCAATTCTCCTGTCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACATGCCACCACACCTGG CTAATTTTTGTATTTTTAGTAGAATCGAGGTTTCATCATGTTGGTCAGGCTGGTCTCAAACTCCTGACT TCAGGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCATGCCCGGCCT AAGAAATACTTTTAAGTATATTTTCATTAGCTAGAATTGCCCAATCTGTGTAGGTATAAATTACTTGGT ATAGGGAGAGAGAAAGCCTATCTTACCTGTTGCTTTCTTACTTGGTGGTAACATCCAGCAGTTAGTCTA TTTATAAACATAATTACTTTTTCACATATGAACCATAAAATATTTAACTTTCTGCTCTATATTGTTTGT TTACCGCTGTATCTCCCACAGCTTGAACAGTACCAAGGTACGTAGTAGGTGCTCAATAAATGACTATTG AATAAATGAACATATCCAACAAATGTTCTCAATGTAAAGGATCAGAGATGCCACATGTTCTCCTTGAT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_005657.4
Synonyms	53BP1; p53BP1; p202; TDRD30
Summary	This gene encodes a protein that functions in the DNA double-strand break repair pathway choice, promoting non-homologous end joining (NHEJ) pathways, and limiting homologous recombination. This protein plays multiple roles in the DNA damage response, including promoting checkpoint signaling following DNA damage, acting as a scaffold for recruitment of DNA damage response proteins to damaged chromatin, and promoting NHEJ pathways by limiting end resection following a double-strand break. These roles are also important during V(D)J recombination, class switch recombination and at unprotected telomeres. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
Locus ID	7158
MW	75.8

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