PSME1 (NM_006263) Human 3' UTR Clone

Specifications

Product Data
Product Name	PSME1 (NM_006263) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HEL-S-129m; IFI5111; PA28A; PA28alpha; REGalpha
ACCN	NM_006263
Insert Size	176 bp
Sequence Data	Insert Sequence (showhide) >SC201702 3’UTR clone of NM_006263 The sequence shown below is from the reference sequence of NM_006263. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGGGGAGAAACAAAGGGAATGATCTATTGAGAGCCCTCTCTCCCATTCTGTGATGAGTACAGCAGAGAC CTTCCTGCTTTTTACTGGGGACTCCAGATTTTCCCCAAACTTGCTTCTGTTGAGATTTTTCCCTCACCT TGCCTCTCAGGCACAATAAATATAGTTATACCACTGCC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006263.4
Synonyms	HEL-S-129m; IFI5111; PA28A; PA28alpha; REGalpha
Summary	The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the alpha subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three alpha and three beta subunits combine to form a heterohexameric ring. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Locus ID	5720
MW	6.5

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