SERPINB6 (NM_004568) Human 3' UTR Clone

Specifications

Product Data
Product Name	SERPINB6 (NM_004568) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3
ACCN	NM_004568
Insert Size	169 bp
Sequence Data	Insert Sequence (showhide) >SC201544 3’UTR clone of NM_004568 The sequence shown below is from the reference sequence of NM_004568. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTCTTCTGCGGCCGCTTTTCCTCTCCGTGAGGACAGGGCAGTCTTGGTGTGCAGCCCCTCTCCTCTCTG TCCCCTGACACTCCACAGTGTGCCTGCAACCCAAGTGGCCTTATCCGTGCAGTGGTGGCAGTTCAGAAA TAAAGGGCCCATTTGTGGGATGCCGCATTCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004568.6
Synonyms	CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3
Summary	The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]
Locus ID	5269
MW	5.9

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