ALAS1 (NM_199166) Human 3' UTR Clone

Specifications

Product Data
Product Name	ALAS1 (NM_199166) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ALAS; ALAS-H; ALAS3; ALASH; MIG4
ACCN	NM_199166
Insert Size	183 bp
Sequence Data	Insert Sequence (showhide) >SC201357 3’UTR clone of NM_199166 The sequence shown below is from the reference sequence of NM_199166. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTGAGCAAGTTGGTATCTGCTCAGGCCTGAGCATGACCTCAATTATTTCACTTAACCCCAGGCCATTAT CATATCCAGATGGTCTTCAGAGTTGTCTTTATATGTGAATTAAGTTATATTAAATTTTAATCTATAGTA AAAACATAGTCCTGGAAATAAATTCTTGCTTAAATGGTGAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_199166.2
Synonyms	ALAS; ALAS-H; ALAS3; ALASH; MIG4
Summary	This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
Locus ID	211
MW	7.1

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