GTF2H4 (NM_001517) Human 3' UTR Clone
CAT#: SC201240
3' UTR clone of general transcription factor IIH polypeptide 4 52kDa (GTF2H4) for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
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经常一起买 (2)
Specifications
Product Data | |
Product Name | GTF2H4 (NM_001517) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | P52; TFB2; TFIIH |
ACCN | NM_001517 |
Insert Size | 153 bp |
Sequence Data |
>SC201240 3’UTR clone of NM_001517
The sequence shown below is from the reference sequence of NM_001517. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTTTGGAAGCGGCAGAAACATAGCTCCTGAGAGCGCGGGACTTGGACACGGACCTCGGCGGGCGGGACT GGGCGGGGCGGGGCATCAGAACTCAGGTGTTTTTTATTTACGCGTCAGGGCTTTTCTTGTTTAATAAAG TTATGATAGCTAGCA AGCGGACCGACTTACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCC CAACCTGCCATCACGAGATTTCGATTCCACCGCCGC |
Restriction Sites | SgfI-RsrII |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_001517.5 |
Synonyms | P52; TFB2; TFIIH |
Summary | Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.[UniProtKB/Swiss-Prot Function] |
Locus ID | 2968 |
MW | 5.7 |
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