SNRPN (NM_022808) Human 3' UTR Clone

Specifications

Product Data
Product Name	SNRPN (NM_022808) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HCERN3; PWCR; PWS; RT-LI; SM-D; sm-N; SMN; SNRNP-N; SNURF-SNRPN
ACCN	NM_022808
Insert Size	309 bp
Sequence Data	Insert Sequence (showhide) >SC201218 3’UTR clone of NM_022808 The sequence shown below is from the reference sequence of NM_022808. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCCCCAGGAATGCGTCCACCAAGACCTTAGCATACTGTTGATCCATCTCAGTCACTTTTTCCCCTGCAA TGCGTCTTGTGAAATTGTGTAGAGTGTTTGTGAGCTTTTTGTTCCCTCATTCTGCATTAATAATAGCTA ATAATAAATGCATAGAGCAATTAAACTGTGAGGTACTGTTGTATATATTTTTTTGCCTGTTGATTTTGA TGAGATCTTAAGTTACTGTGGATGAGGGTGATGCCTATTAAGCAGTTGATTCAAATCATATTCTCTTTA ATTCTTAGGATAAAAAGGTTTTCTGCTATCTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_022808.5
Synonyms	HCERN3; PWCR; PWS; RT-LI; SM-D; sm-N; SMN; SNRNP-N; SNURF-SNRPN
Summary	This gene is located within the Prader-Willi Syndrome critical region on chromosome 15 and is imprinted and expressed from the paternal allele. It encodes a component of the small nuclear ribonucleoprotein complex, which functions in pre-mRNA processing and may contribute to tissue-specific alternative splicing. Alternative promoter use and alternative splicing result in a multitude of transcript variants encoding the same protein. Transcript variants that initiate at the CpG island-associated imprinting center may be bicistronic and also encode the SNRPN upstream reading frame protein (SNURF) from an upstream open reading frame. In addition, long spliced transcripts for small nucleolar RNA host gene 14 (SNHG14) may originate from the promoters at this locus and share exons with this gene. Alterations in this region are associated with parental imprint switch failure, which may cause Angelman syndrome or Prader-Willi syndrome. [provided by RefSeq, Mar 2017]
Locus ID	6638
MW	11.8

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