HLAF (HLA-F) (NM_018950) Human 3' UTR Clone

Specifications

Product Data
Product Name	HLAF (HLA-F) (NM_018950) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CDA12; HLA-5.4; HLA-CDA12; HLAF
ACCN	NM_018950
Insert Size	147 bp
Sequence Data	Insert Sequence (showhide) >SC201186 3’UTR clone of NM_018950 The sequence shown below is from the reference sequence of NM_018950. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGAGGGAGCTACTCTCAGGCTGCAGTGTGAGACAGCTTCCTTGTGTGGGACTGAGAAGCAAGATATCAA TGTAGCAGAATTGCACTTGTGCCTCACGAACATACATAAATTTTAAAAATAAAGAATAAAAATATATCT TTTTATAGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_018950.3
Synonyms	CDA12; HLA-5.4; HLA-CDA12; HLAF
Summary	This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain. [provided by RefSeq, Jul 2008]
Locus ID	3134
MW	5.8

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