Major Basic Protein (PRG2) (NM_002728) Human 3' UTR Clone

Specifications

Product Data
Product Name	Major Basic Protein (PRG2) (NM_002728) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BMPG; MBP; MBP1; proMBP
ACCN	NM_002728
Insert Size	725 bp
Sequence Data	Insert Sequence (showhide) >SC201102 3’UTR clone of NM_002728 The sequence shown below is from the reference sequence of NM_002728. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGAAGACTTCCTTTCATCTGTTCCTACTGAGCTGGTCCCAGCCAGCAGTTCAGAGCTGCCCTCTCCTGG GCAGCTGCCTCCCCTCCTCTGCTTGCCATCCCTCCCTCCACCTCCCTGCAATAAAATGGGTTTTACTGA AATGGATTTATTTTCTCCTCTGATCGCGGATCCACTCTGCTTAGCCCTCATTGAAACTTCTTCCTTATC ATCTCTCCCCACACCACAACTTTCATAGAAGTGTCAGAAGCTACTACTCCTTGAGGAGGAGGATGGAGG GTGGAGTTGGGTCTATGGAGCCTTTTGGAGATGGAGGAATGGGCTCAGCTAGTTCTCTTCATAGAACAC CTGATTACTGGGCACCTGCATAGTGCTGCCAGGACCTTTCAAGGTTGTAGGTAGACTCCCAATGGCCCA GTTTGCATCTCTGTAACCAAAGGCCTTTTCTCTCTCTCTCTCCAACCCCAGAACTGTGGTTGGTTTTAT ATGTAAGGAAGTTAACATGTCCCTGGGAACAGTCCACAACATTCAGGAATGAATGTATAAGTACCGCAA TCCCCGGCCCCTCAAGTGGAATAAATCTAACATGTATTGGGCACCATTTCCCAGTGGCCTGCTGTGGTA GTTGGCCTTATTCCATGCATTTTTATGGGCTGCCTTCCCTTCCTCAACTGCATTCTCTGCTCCTTCCTA CTCTCTGCAACTCCCAAATAAACACTTGTACGCAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002728.6
Synonyms	BMPG; MBP; MBP1; proMBP
Summary	The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
Locus ID	5553
MW	26.3

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