Peroxiredoxin 2 (PRDX2) (NM_181738) Human 3' UTR Clone

Specifications

Product Data
Product Name	Peroxiredoxin 2 (PRDX2) (NM_181738) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	NKEFB; PRP; PRX2; PRXII; PTX1; TDPX1; TPX1; TSA
ACCN	NM_181738
Insert Size	161 bp
Sequence Data	Insert Sequence (showhide) >SC201096 3’UTR clone of NM_181738 The sequence shown below is from the reference sequence of NM_181738. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTAAGGATGATGACAGTAATTAGCATTTGACAACTAGTTGCCTGGTATATAGAGTTGCAGATGCAACTC AGATGCAACTCTATCTACTCTATGTACTTAGTTCCCAGGAGGGAGGCTGTGCTGCCCTATTTCATGAAG ATGGAAACTCCAGTTCACCGAAG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_181738.1
Synonyms	NKEFB; PRP; PRX2; PRXII; PTX1; TDPX1; TPX1; TSA
Summary	This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]
Locus ID	7001
MW	6.5

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