NPR2L (NPRL2) (NM_006545) Human 3' UTR Clone

Specifications

Product Data
Product Name	NPR2L (NPRL2) (NM_006545) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	FFEVF2; NPR2; NPR2L; TUSC4
ACCN	NM_006545
Insert Size	306 bp
Sequence Data	Insert Sequence (showhide) >SC201005 3’UTR clone of NM_006545 The sequence shown below is from the reference sequence of NM_006545. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GACCCCAACATCATCATCTGCTGGAAGTGAGGCTGGTAGTGACTGGATGGACACATTGCTGTGGGTAGT CCCTCCTACTAGGAGGCTTGTCATACTGTCTAGAGGTTGACTCTTAGTTCTGTAAATAAAGACATCCAT TTCAAACAGCCTTTATTGAGTGCTGTTTCTGGGCCAGCCGTGGGAGACCCAGCAGTGAATGAAATAGCC ACGAGCCGTGGGCTAGATCGCCATCTGGTGGGCAGGACCGACAATCGACAAATAAAAGTGCCGGTTAAT TACAAAAAAAAAAAAAAAAAAAAAAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006545.5
Synonyms	FFEVF2; NPR2; NPR2L; TUSC4
Summary	As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.[UniProtKB/Swiss-Prot Function]
Locus ID	10641
MW	11.3

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.