Caspase 5 (CASP5) (NM_001136112) Human 3' UTR Clone

Specifications

Product Data
Product Name	Caspase 5 (CASP5) (NM_001136112) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ICE(rel)III; ICEREL-III; ICH-3
ACCN	NM_001136112
Insert Size	139 bp
Sequence Data	Insert Sequence (showhide) >SC200803 3’UTR clone of NM_001136112 The sequence shown below is from the reference sequence of NM_001136112. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGAGATTTCTACCTCTTTCCTGGCAATTGAAAATGAAACCACAGGCAGCCCAGCCCTCCTCTGTCAACA TCAAAGAGCACATTTACCAGTATAGCTTGCATAGTCAATATTTGGTATTTCAATAAAAGTAAAGACTGTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001136112.3
Synonyms	ICE(rel)III; ICEREL-III; ICH-3
Summary	This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]
Locus ID	838
MW	5.3

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