TOP3B (NM_003935) Human 3' UTR Clone

Specifications

Product Data
Product Name	TOP3B (NM_003935) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	TOP3B1
ACCN	NM_003935
Insert Size	119 bp
Sequence Data	Insert Sequence (showhide) >SC200620 3’UTR clone of NM_003935 The sequence shown below is from the reference sequence of NM_003935. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATGTCAGCCCTGGCCGCCTACTTTGTATGATGACCCTGTCCTCCCTCACCCAGGCTGCAGTGCCATGCA GACACCTCATGGCACTTCAAACTATTAAAATGCATTTTATCTTATCCAGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003935.5
Synonyms	TOP3B1
Summary	This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Low expression of this gene may be related to higher survival rates in breast cancer patients. This gene has a pseudogene on chromosome 22. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Aug 2013]
Locus ID	8940
MW	4.4

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