hemoglobin subunit gamma 1 (HBG1) (NM_000559) Human 3' UTR Clone
CAT#: SC200439
3' UTR clone of hemoglobin gamma A (HBG1) for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
Cited in 2 publications. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | hemoglobin subunit gamma 1 (HBG1) (NM_000559) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | HBG-T2; HBGA; HBGR; HSGGL1; PRO2979 |
ACCN | NM_000559 |
Insert Size | 120 bp |
Sequence Data |
>SC200439 3’UTR clone of NM_000559
The sequence shown below is from the reference sequence of NM_000559. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCCAGTGCCCTGTCCTCCAGATACCACTGAGCTCACTGCCCATGATTCAGAGCTTTCAAGGATAGGCTT TATTCTGCAAGCAATACAAATAATAAATCTATTCTGCTGAGAGATCACACA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_000559.3 |
Synonyms | HBG-T2; HBGA; HBGR; HSGGL1; PRO2979 |
Summary | The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008] |
Locus ID | 3047 |
MW | 4.6 |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
---|
Stable expression of miR-34a mediates fetal hemoglobin induction in K562 cells
,Ward, CM;Li, B;Pace, BS;,
Exp. Biol. Med. (Maywood)
,PubMed ID 26940952
[HBG1]
|
MicroRNA-96 Directly Inhibits ?-Globin Expression in Human Erythropoiesis
,null,
PLoS ONE
,PubMed ID 21829531
[HBG1]
|
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