ADAM22 (NM_004194) Human 3' UTR Clone

Specifications

Product Data
Product Name	ADAM22 (NM_004194) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ADAM 22; DEE61; EIEE61; MDC2
ACCN	NM_004194
Insert Size	118 bp
Sequence Data	Insert Sequence (showhide) >SC200412 3’UTR clone of NM_004194 The sequence shown below is from the reference sequence of NM_004194. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTTAGACCTCGGTCTAATTCAACTGAGTAAGTCTGAACCTCTAATGGAAAAAGGCACTCCAAGGTCCTG TGCAAATAGTGTCAAAAGTAAATTAAGCAGATAGTCAAAGAACTGTAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004194.5
Synonyms	ADAM 22; DEE61; EIEE61; MDC2
Summary	This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.[provided by RefSeq, Dec 2010]
Locus ID	53616
MW	4.4

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