MYH (MUTYH) (NM_001048174) Human 3' UTR Clone
CAT#: SC200339
3' UTR clone of mutY homolog (E. coli) (MUTYH) transcript variant beta3 for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
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Specifications
Product Data | |
Product Name | MYH (MUTYH) (NM_001048174) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | MYH |
ACCN | NM_001048174 |
Insert Size | 94 bp |
Sequence Data |
>SC200339 3’UTR clone of NM_001048174
The sequence shown below is from the reference sequence of NM_001048174. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCACACAGCCTCAACAGTGCAGCCCAGTGACACCTCTGAAAGCCCCCATTCCCTGAGAATCCTGTTGTT AGTAAAGTGCTTATTTTTGTAGTTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_001048174.2 |
Synonyms | MYH |
Summary | This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017] |
Locus ID | 4595 |
MW | 3.4 |
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