Adenylosuccinate Lyase (ADSL) (NM_000026) Human 3' UTR Clone

Specifications

Product Data
Product Name	Adenylosuccinate Lyase (ADSL) (NM_000026) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AMPS; ASASE; ASL
ACCN	NM_000026
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC200010 3’UTR clone of NM_000026 The sequence shown below is from the reference sequence of NM_000026. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCT GAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAG CACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGA GCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCAT ATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCT GGTCCTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAA TGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAAGTGATGAAGTTTGGAACTACAGTAAAT ACTTAAAAAAAAAAAAAAAAAGAACCAAACCCTGATGTGACCATCAGGCTGATTGAGCTGAAGTTGTGC CCAAGCTCATTTCATCTTTTGATAAGGCTTATACAGCAGGGAAATGCTAATTGAGTATATTGATTTCAT CAGGGCCGCTGACAGTCTTTATTCCTTGTTGCATGGATTTTGTTGTTGAGGCTTGCTCTGTCACCCAGA CTAGAGTGCAGTAGCACAATCTTGGCTCACTGCAACCTCCGCCTCTCAGGTTCAAGCGATTCTCCAGCC TCAGCCTCCCAAGTAGCTGGGATTACAGGCGCCTGCCGCCATGCCTGGCTAATTTTTGTATTTTTAGAC GGGATGGAGTTTTGCCATGTTGGGCGGGCTGGTCTTGAACTCCTGACCTCAAGTGATCCGCCCATCTCA GCCTCCCAAAGTTCTGGGATTATAGACATGAGCCACCACACCCAGCCTAATCTTGTTTTCTTTTTTTAC TTGTTTACAGTGTAAGCAAGTGCCATTGGACAAGAACGTTGTCTGTGTCATTCCTTGTTGTATTTCCAA TAGCAAGAGCACATCAGATACTTGGCAACTAGGCAGTCTTCCAGCTTCTGCCACTGCGCCCGACTTCCT TGTTGCATGGATTTATAGCTGATTGAAGCAACTGTAGCCAAAGATTGAGTTAATTACCTACCTGCCAGG AGAGCACTAGTGTTATTTAGCCCATTCTCATCCTACATATTTTTCGGCATAGATGAAAATGAAAGCTTT TGTTTATCAGATTTGCAGATGACACAAAACTGGGAGAATTAACAAGTATGTTTATTTGGTAAAATAAGT TTTCATCTCTAACCTAAATCGGCTGAAATGATGTGTCCTAAACTAGAGGAAAAAGTTAATAAAGATCAA TGTAAATAAGTTAATCTTAAACTCAGTATGCACCAGAACTGAGAGAAGACTGTTTTAGGAGGTGTTAAT GGTTGTCCAGTGCCCAAAAAGCCACCAGAGGCTTACTGCTCCGCACTCTTGGCATTACATTCAATTTTG GATACCCAGTCTGAGGAATAGAGATGAACTGGAGAGCCAACCTCCAAAAAGATCTTGTGGTGGAGGAAT GTTAGGGCTCTTTATCCTATACAGAAGAAAACTCCTCGGCACTTCAAATATTGCCAGGTGCAGGAAGAG TGACTTGATTGTGTGTTGCCCCAAGAGACACACTGAGCTCAATACCCATTACTGAGACTGGCTTGGGGC CAGACATTGGAACCACTGAGATTAGCAACCTACACTCAATCCCCCAGGTCAGGCAGAAGCTGGAAGACT GCCTCGTTAGGAATGTTGTGAGGGAGAGGAGGCTGAATCGGTTCCAGTTTTATTTAAAAGTAGCCAGGA AATCAGGTTGCGATGATGCGCATTTACAGTCCCAGCTACTTGGGAAGCTGAGGCGATAGGGTCACTTGA GCCCAAGAGTTTAGTCCAGGCTGGGTGACAGCGAGCCCTTGTCACTTAAAGCCAACCTAAGAGAAGAG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000026.4
Synonyms	AMPS; ASASE; ASL
Summary	The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]
Locus ID	158
MW	75.8

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