Mouse Tgfb1 ELISA KIT (96 T)
CNY 3,200.00
货期*
3周
规格
Specifications
Product Data | |
Description | Mouse TGF-β1 ELISA KIT |
Size | 96 T |
Format | 96-well strip plate |
Assay Type | Solid Phase Sandwich ELISA |
Assay Length | 4 hours |
Signal | Colorimetric |
Curve Range | 15.625-1000pg/ml |
Sample Type | Serum, plasma, Cell culture supernatant |
Sample Volume | 100 uL |
Specificity | This assay recognizes both natural and recombinant mouse TGF-β1. |
Sensitivity | 15 pg/ml |
Reactivity | Mouse |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | Transforming growth factor beta (TGF-β) proteins (including the three closely related mammalian isoforms TGF-β1, -2 and -3) are pleiotropic cytokines that regulate extracellular matrix production, wound healing, immune functions, cell proliferation and differentiation. They belong to the large TGF-β superfamily, which also includes the activins/inhibins/MIS, bone morphogenetic proteins (BMPs), growth / differentiation factors (GDFs), Lefty1 and 2, and the distantly related GDNF family of neurotrophic factors. All family members show a characteristic cysteine-knot that is formed from multiple intrachain disulfide bonds. The mouse, rat, porcine and canine TGF-β1 cDNAs encode a 390 amino acid (aa) residue precursor that contains a 29 aa signal peptide and a 361 aa pro-protein. The pro-protein for each species is proteolytically processed via a furin-like convertase to generate an N-terminal 249 aa latency-associated peptide (LAP), and a C-terminal 112 aa mature TGF-β1. Both LAP and mature TGF-β1 exist as disulfide-linked homodimers. |
Gene Symbol | Tgfb1 |
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