Human Cystatin C (CST3) ELISA KIT (96 T)

Specifications

Product Data
Description	Human Cystatin C ELISA KIT
Size	96 T
Format	96-well strip plate
Assay Type	Solid Phase Sandwich ELISA
Assay Length	4 hours
Signal	Colorimetric
Curve Range	31.25-2000pg/ml
Sample Type	Serum, plasma, Cell culture supernatant
Sample Volume	100 uL
Specificity	This assay recognizes both natural and recombinant human Cystatin C.
Sensitivity	15 pg/ml
Reactivity	Human
Interference	No significant interference observed with available related molecules.
Components	Microwell Plate - antibody coated 96-well Microplate (8 wells ×12 strips),1 plate Standard - lyophilized,2000 pg/ml upon reconstitution,2 vials Concentrated Biotin-Conjugated antibody(100X) - 120 ul/vial,1 vials Concentrated Streptavidin-HRP solution(100X) - 120 ul/vial,1 vial Standard /Sample Diluent - 16 ml/vial,1 bottle Biotin-Conjugate antibody Diluent - 16 ml/vial,1 bottle Streptavidin-HRP Diluent - 16 ml/vial,1 bottle Wash Buffer Concentrate (20x) - 30 ml/vial,1 bottle Substrate Solution - 12 ml/vial,1 bottle Stop Solution - 12 ml/vial,1 bottle Plate Cover Seals,4 pieces
Background	Cystatin C (gene name CST3) is a secreted cysteine protease inhibitor that belongs to the cystatin superfamily. It is a protein of 120 amino acids and approximately 13 kDa in its non-glycosylated form; a glycosylated form is reported in rat, but not in mouse. Mature human Cystatin C shares 72% amino acid sequence identity with mouse and rat Cystatin C. Cystatin C is susceptible to endoprotease cleavage producing N-terminally truncated forms. Cysteine proteases of the papain family, such as Cathepsins B, H, K, L, and S, are the major targets for Cystatin C. Cystatin C is involved in several disease processes through its regulation of cysteine protease activity. In humans, high circulating Cystatin C in the presence of apparently normal kidney function is associated with coronary artery and cardiovascular disease risk.
Gene Symbol	CST3

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