Human AKT2 ELISA Kit 1 x 96

Specifications

Product Data
Description	Human AKT2 ELISA Kit 1 x 96
Size	1 x 96 wells
Format	8x12 divisible strips
Assay Type	Sandwich
Assay Length	3.5 hours incubations; 0.5 hour washing and analyzing samples
Signal	Colorimetric
Curve Range	0.156-10ng/ml
Sample Type	Human serum, plasma, and other biological fluids.
Sample Volume	100µl
Specificity	This kit is used for quantitative detection of AKT2
Sensitivity	60pg/ml
Reactivity	Human
Cross Reactivity	There is no detectable cross-reactivity with other relevant proteins.
Interference	No significant interference observed with available related molecules.
Components	AKT2 Monoclonal Antibody Coated 96-well Plate in foil pouch with desiccant|1 plate Human AKT2 Standard (500ng/ml)|0.1 mL 100x Biotin conjugated AKT2 Detection Antibody|0.12 mL 100x SA-HRP Conjugate0.12 mL Assay Buffer|40 mL Sample Diluent|20 mL Wash Buffer Concentrate 20X|60 mL TMB Substrate|12 mL Stop Solution|12 mL Plate Sealer|3 pieces
Background	AKT2, also known as RAC-beta serine/threonine-protein kinase, is an enzyme that in humans is encoded by the AKT2 gene. It influences metabolite storage as part of the insulin signal transduction pathway. AKT2 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) that belong to the AKT subfamily. AKT represents an important signaling hub, modulating many processes including metabolism, proliferation, cell survival, growth and angiogenesis by phosphorylating a range of downstream substrates in response to growth factor stimulation. Akt2 is associated with the development of human cancers. Amplification or high levels of expression of Akt2 are frequently found in human pancreatic, lung, colorectal, ovarian, and breast cancers, and high Akt2 expression levels are positively correlated with the aggressiveness of cancer or poor survival rates in colorectal, ovarian, and breast cancers. AKT2 constitutes a prognostic marker of poor clinical outcomes in breast cancer, ovarian cancer, lung adenocarcinoma, and hepatocellular carcinoma.
Gene Symbol	AKT2
Standard Curve	Data image of Human AKT2 ELISA Kit.

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