Human GFAP ELISA KIT (1 x 96 wells)

Specifications

Product Data
Description	Human GFAP ELISA KIT (1 x 96 wells)
Size	1 x 96 wells
Format	8x12 divisible strips
Assay Type	Sandwich
Assay Length	4 hours incubations; 0.5 hour washing and analyzing samples
Signal	Colorimetric
Curve Range	0.78ng/ml-50ng/ml
Sample Type	Human serum, plasma and other biological fluids.
Sample Volume	100µl
Specificity	This kit is used for quantitative detection of Human GFAP
Sensitivity	85pg/ml
Reactivity	Human
Cross Reactivity	There is no detectable cross-reactivity with other relevant proteins.
Interference	No significant interference observed with available related molecules.
Components	GFAP Antibody Coated 96-well Plate in foil pouch with desiccant|1 plate Recombinant Human GFAP Standard (2.5µg/ml)|0.1 mL 100x HRP conjugated GFAP Detection Antibody|0.12 mL Assay Buffer|60 mL Wash Buffer Concentrate 20X|60 mL TMB Substrate|12 mL Stop Solution|12 mL Plate Sealer2 pieces
Background	Glial fibrillary acidic protein (GFAP) is a type III intermediate filament (IF) protein that is expressed by numerous cell types of the central nervous system (CNS), including astrocytes and ependymal cells during development. GFAP has also been found to be expressed in glomeruli and peritubular fibroblasts, Leydig cells of the testis, keratinocytes, osteocytes and chondrocytes. It has been shown to be important in the pathogenesis of Alexander disease and in repair after CNS injury. Decreases in GFAP expression have been reported in Down's syndrome, schizophrenia, bipolar disorder and depression. GFAP levels are already used as a marker for the activation of astrocytes (AS) following injury or stress in the CNS. Serum GFAP shows promise as a biomarker of disease severity in frontotemporal lobar degeneration (FTLD), and might be a suitable multiple sclerosis progression biomarker. In addition, GFAP has been used as a classical marker of astrocytoma and a diagnostic biomarker for glioblastoma multiforme (GBM).
Gene Symbol	GFAP

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