Rat Stc2 ELISA KIT (1 x 96 wells)
CAT#: EA102673
For quantitative detection of rat STC2 in cell culture supernates, serum and plasma (heparin).
CNY 5,000.00
货期*
3周
规格
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Specifications
Product Data | |
Description | For quantitative detection of rat STC2 in cell culture supernates, serum and plasma (heparin). |
Size | 1 x 96 wells |
Format | 8x12 divisible strips |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Rat STC2 |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 156pg/ml-10000pg/ml |
Specificity | This kit is used for quantitative detection of Rat STC2 |
Sensitivity | <50pg/ml |
Reactivity | Rat |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Components |
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Background | Stanniocalcin-2 is a protein that in humans is encoded by the STC2 gene. It is mapped to 10q12. This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. STC2 has opposite effects on calcium and phosphate homeostasis as compared to Stc1. |
Gene Symbol | Stc2 |
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